A vaccine that prevents a painful rash may also protect your brain as you age. A large new study suggests the shingles vaccine could reduce the risk of vascular dementia by nearly 50%, according to findings presented at IDWeek 2025 in Atlanta and reported by Fox News. Researchers at Case Western Reserve University reviewed health records from 174,000 adults across the U.S. who were vaccinated. They followed participants for up to seven years and saw major differences compared with those who didn’t get the shot.
Study Finds Lower Risk of Dementia and Heart Disease
The research team found that adults who received the shingles vaccine had about half the risk of developing vascular dementia, which is caused by reduced blood flow to the brain. The vaccinated group also had a 25% lower risk of heart attack or stroke, a 27% reduced risk of blood clots, and a 21% lower risk of death from any cause. These statistics were shared in a news release from the Infectious Diseases Society of America.
Why a Shingles Vaccine Could Help Protect the Brain
Shingles happens when the chickenpox virus, called varicella-zoster, becomes active again in the body. It causes a blistering rash and severe nerve pain. But experts say the virus may also increase inflammation, which is linked to both heart problems and cognitive decline. Preventing shingles could reduce that harmful inflammation before it starts. “It is very comforting to know that the shingles vaccine is certainly associated with overall significant health benefits beyond its intended purpose,” said Dr. Aaron Glatt, infectious disease physician at Mount Sinai South Nassau, in an interview with Fox News Digital.
Who Should Get the Shingles Vaccine?
The CDC recommends two doses of the shingles vaccine (Shingrix) for adults 50 and older, as well as adults 19+ with weakened immune systems. While more research is needed to prove exactly how the vaccine supports brain health, experts say this is one more strong reason to get protected — for your long-term health and peace of mind.
